Depo-Medrone is a long-acting steroid injection that’s given to reduce inflammation.
Depo-Medrone injection contains the active ingredient methylprednisolone,
Methylprednisolone reduces inflammation by stopping cells from releasing substances that are involved in producing immune and allergic responses. This can help control a wide number of disease states that involve excessive inflammation, including severe allergic reactions, inflammation of the lungs in asthma and inflammation of the joints in arthritis.
It’s hard to predict how likely you are to get side effects from Depo-Medrone injection. It depends how many injections you have and any conditions you have that might make you more susceptible to problems. Side effects become more likely with higher doses and longer treatment.
Side effects are much less likely with joint injections, because the methylprednisolone mainly stays in the joint and is very slowly absorbed into rest of the body. The main side effects following joint injection are flushing or dizziness and a temporary increase in pain and swelling for the first 24 to 48 hours and possibly some slight wasting of tissue or thinning of skin at the injection site. There is also a small risk of introducing infection into the joint, so it’s important to tell your doctor if you have a distinct increase in pain, accompanied by swelling, further restriction of joint movement, fever and feeling generally unwell after your injection.